Amir Dehsarvi

Amir Dehsarvi

I am a researcher interested in the application of machine learning techniques for the analysis of medical data.

ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels

Published in JAMA Neurology, vol 80, issue 12., 2023

Recommended citation: Steward, A., Biel, D., Dewenter, A., Roemer, S., Wagner, F., Dehsarvi, A., Rathore, S., Otero Svaldi, D., Higgins, I., Brendel, M., Dichgans, M., Shcherbinin, S., Ewers, M., Franzmeier, N. (2023). ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels. JAMA Neurol. 80(12): 1295-1306. doi: 10.1001/jamaneurol.2023.4038. https://doi.org/10.1001/jamaneurol.2023.4038

This paper explores the role of ApoE4 in the connectivity-mediated spreading of tau pathology at lower amyloid levels in the brain. The study delves into the intricate relationships between genetic factors and neurodegenerative processes, contributing valuable insights into the mechanisms underlying Alzheimer’s disease progression.

Download paper here

Recommended citation: Steward, A., Biel, D., Dewenter, A., Roemer, S., Wagner, F., Dehsarvi, A., Rathore, S., Otero Svaldi, D., Higgins, I., Brendel, M., Dichgans, M., Shcherbinin, S., Ewers, M., Franzmeier, N. (2023). ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels. JAMA Neurol. 80(12): 1295-1306. doi: 10.1001/jamaneurol.2023.4038.