Neuroinflammation Parallels 18F-PI-2620 Positron Emission Tomography Patterns in Primary 4-Repeat Tauopathies

Published in Movement Disorders, 2024

Recommended citation: Malpetti, M., Roemer, S.N., Harris, S., Gross, M., Gnörich, J., Stephens, A., Dewenter, A., Steward, A., Biel, D., Dehsarvi, A., Wagner, F., Müller, A., Koglin, N., Weidinger, E., Palleis, C., Katzdobler, S., Rupprecht, R., Perneczky, R., Rauchmann, B.-S., Levin, J., Höglinger, G.U., Brendel, M., Franzmeier, N. (2024). Neuroinflammation Parallels 18F-PI-2620 Positron Emission Tomography Patterns in Primary 4-Repeat Tauopathies. Movement Disorders. doi: 10.1002/mds.29924. https://doi.org/10.1002/mds.29924

This study explores the relationship between neuroinflammation and tau pathology in primary 4-repeat tauopathies using PET imaging. The research investigates whether microglial activation progresses in similar spatial patterns as tau spreads across interconnected brain regions, and if the degree of microglial activation parallels tau pathology spreading.

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Recommended citation: Malpetti, M., Roemer, S.N., Harris, S., Gross, M., Gnörich, J., Stephens, A., Dewenter, A., Steward, A., Biel, D., Dehsarvi, A., Wagner, F., Müller, A., Koglin, N., Weidinger, E., Palleis, C., Katzdobler, S., Rupprecht, R., Perneczky, R., Rauchmann, B.-S., Levin, J., Höglinger, G.U., Brendel, M., Franzmeier, N. (2024). Neuroinflammation Parallels 18F-PI-2620 Positron Emission Tomography Patterns in Primary 4-Repeat Tauopathies. Movement Disorders. doi: 10.1002/mds.29924.