Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease
Nature Communications, vol 15, issue 1. · January 2024
This paper investigates the association between elevated cerebrospinal fluid (CSF) GAP-43 levels and the accelerated accumulation and spread of tau pathology in Alzheimer’s disease. The findings provide critical insights into the biomarkers and mechanisms driving disease progression, highlighting potential targets for therapeutic intervention.
Recommended citation: Franzmeier, N., Dehsarvi, A., Steward, A., Biel, D., Dewenter, A., Roemer, S.N., Wagner, F., Groß, M., Brendel, M., Moscoso, A., Arunachalam, P., Blennow, K., Zetterberg, H., Ewers, M., Schöll, M. (2024). Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer’s disease. Nat Commun. 15(1): 202. doi: 10.1038/s41467-023-44374-w.
Recommended citation
Franzmeier, N., Dehsarvi, A., Steward, A., Biel, D., Dewenter, A., Roemer, S.N., Wagner, F., Gross, M., Brendel, M., Moscoso, A., Arunachalam, P., Blennow, K., Zetterberg, H., Ewers, M., Schoell, M. (2024). Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease. Nat Commun. 15(1): 202. doi: 10.1038/s41467-023-44374-w.